This code defines a Python function named `dna2aa` that translates...
August 29, 2025 at 06:54 AM
This code defines a Python function named dna2aa
that translates a DNA sequence (string) into a corresponding amino acid sequence (string) using codons.
Explanation:
-
Input: The function takes one argument,
dna_str
, which is a string representing a DNA sequence consisting of nucleotide bases (A, T, C, G). -
Output: The function returns a string,
aa_str
, which represents the amino acid sequence derived from the DNA sequence. -
Logic Breakdown:
aa_str = ""
: Initializes an empty string to build the translated amino acid sequence.for i in range(0, len(dna_str), 3)
: Iterates through the DNA sequence in chunks (frames) of 3 nucleotides (which form a codon).codon = dna_str[i:i+3]
: Extracts a codon (group of 3 nucleotides).aa = codon2aa.get(codon, "X")
: Looks up the amino acid corresponding to this codon in a dictionarycodon2aa
.- If the codon is not found in the dictionary, it defaults to "X" (unknown amino acid).
aa_str += aa
: Appends the derived amino acid to theaa_str
.
-
Return Statement: After processing all codons, the function returns the full amino acid sequence.
Assumptions:
codon2aa
is assumed to be a predefined dictionary that maps 3-letter DNA codons to their respective single-letter amino acid codes. For example,{'ATG': 'M', 'TGG': 'W', 'TAA': '*', ...}
.- If the DNA sequence length is not a multiple of 3, the last one or two remaining bases will be ignored because slicing (
dna_str[i:i+3]
) stops at the end of the string.
Example Usage:
codon2aa = {
'ATG': 'M', 'TGG': 'W', 'TAA': '*', 'TAG': '*', 'TGA': '*',
'GCT': 'A', 'GCC': 'A', 'GCA': 'A', 'GCG': 'A'
# More codons...
}
dna_sequence = "ATGGCTTAA"
amino_acid_sequence = dna2aa(dna_sequence)
print(amino_acid_sequence)
# Output: "MA*"
Summary:
The dna2aa
function performs codon-to-amino-acid translation of a DNA sequence using a codon lookup dictionary (codon2aa
) and returns the corresponding amino acid sequence.
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