This code defines a Python function, `dna2aa`, which converts a...

August 29, 2025 at 06:54 AM

def dna2aa(dna_str): aa_str = "" for i in range(0, len(dna_str), 3): codon = dna_str[i:i+3] aa = codon2aa.get(codon, "X") aa_str += aa return aa_str

This code defines a Python function, dna2aa, which converts a DNA sequence (dna_str) into its corresponding amino acid sequence (aa_str). Here's a breakdown of what the code does:

  1. Parameters and Initialization:

    • The function takes a single string parameter, dna_str, which should represent a DNA sequence.
    • It initializes an empty string aa_str to store the resulting amino acid sequence.
  2. Iterating Over DNA Sequence in Codons:

    • Using range(0, len(dna_str), 3), the function iterates over the DNA sequence in steps of 3 characters at a time. Each group of 3 nucleotides is called a "codon".
  3. Extracting Codons:

    • For each iteration, it extracts a substring of length 3, codon = dna_str[i:i+3].
  4. Codon to Amino Acid Mapping:

    • The function uses a dictionary named codon2aa to map each codon to a specific amino acid. This dictionary is expected to exist outside the function but is not defined in the provided code snippet.
    • If the codon exists in the dictionary codon2aa, it retrieves the corresponding amino acid (aa).
    • If the codon does not exist in codon2aa, it defaults to the value "X" (likely representing an unknown codon).
  5. Appending the Amino Acid:

    • The translated amino acid is appended to aa_str.
  6. Returning the Amino Acid Sequence:

    • Once all the codons in dna_str have been processed, the function returns the resulting aa_str, which is the amino acid sequence corresponding to the input DNA sequence.

Example Usage (if codon2aa is defined):

Assume codon2aa = {"ATG": "M", "TGG": "W", "TAA": "*", "TAG": "*", "TGA": "*"}.

Input:

dna2aa("ATGTGGTAA")

Steps:

  • Process codons: "ATG", "TGG", and "TAA".
  • Translate to amino acids: M, W, and *.

Output:

"MW*"

If an unknown codon (e.g., "AAA" not in codon2aa) appears, it will be translated as "X".

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